#FOTD211 Tiny Robots Deliver Antibiotics

#FOTD211 Tiny Robots Deliver Antibiotics


– Fact of the day!
– Fact of the day. Hello, hi, and welcome to
fact of the day with me Mark Lotsu. Tiny robots used to deliver antibiotics. So, Joseph Wang and his team at the University of California, they’ve been using these
tiny, tiny itty-bitty robots to deliver antibiotics to
help treat stomach ulcers within mice. The stomach ulcers are caused by bacteria so the antibiotics are
effective against bacteria. One of the problems that
we have with antibiotics is that the antibiotics
can actually be destroyed by the stomach acid
before they’re effective in killing off or destroying a bacteria. So some human patients
who have stomach ulcers, they take medications
that have been augmented with something called a
protein pump inhibitor. And what this does is it
reduces amount of gastric juice, the amount of stomach acid
that’s produced, which means that the antibiotics are
going to be more effective. The problem we have
here is the side effects include things like anxiety,
headaches, and diarrhoea. So these robots, they’re about
the width of the human hair, and what they do is they
have these micro-matches, and they deliver the
antibiotics every single day for five days, and it’s
shown they’re more effective than normal antibiotic tablets. The robot is made of
up a core of magnesium surrounded by these multiple layers, and the multiple layers allow
it to survive and deliver the treatment as each of the
layer’s slowly breaks down. When they’re in the stomach,
the micro-match is used to free proteins found in the stomach
acids to produce a stream or jet of hydrogen bubbles which propels the little robots around. And that means it can evenly
distribute the antibiotics or parts of the stomach,
preferably to the size of the stomach where most of the
bacteria will be concentrated. It also helps to reduce the
acidity of the stomach acid, and by helping to reduce the
acidity of the stomach acid it means that the antibiotics
can actually be more effective. And the micro-match can
dissolve and 24 hours later, the stomach acid goes back
up to it’s original acidity, and everything is back to normal. So that’s how tiny robots
can deliver antibiotics. Thanks for watching. Love you, bye, love you, bye. Love you, bye.

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