The Spiral Method, how does it work?

The Spiral method How does it work? The Spiral method is a standardized method of enumeration via plating This plating follows an Archimedes spiral logarithmically decreasing from the center of the dish towards the periphery. It allows the plating of 4 dilutions on the same fish, by spreading a decreasing amount of sample with known […]

Bacterial Isolation on Petri Dish – Biology Lab Techniques

Start by cleaning and sterilizing the workspace. Spray once with 10% Milton and wipe thoroughly using clean tissue paper. Repeat twice, but with 70% ethanol. A diluted 70% solution of ethanol is actually a more potent disinfecting agent than pure ethanol. One of the goals of growing Bacteria on solid medium is to grow individual […]

What Makes Blowfish Toxic? | Microbe Minute

ED YONG: These tropical fish have a signature defense. But inside some blowfish is even more protection– a potent toxin made by microbes. [MUSIC PLAYING] The inflated size of blowfish can thwart predators. [MUSIC PLAYING] Those with spines have even more security. [MUSIC PLAYING] And there’s a third defense that some of these fish share. […]

Nature’s Cutest Symbiosis: The Bobtail Squid | I Contain Multitudes

[MUSIC PLAYING] Hello. Yes, it’s me, right here. Being able to turn invisible, or at the very least being incredibly well-camouflaged, is incredibly useful, especially if I was a spy. I’m not a spy. For me, it would be really fun to be able to disappear from view on a whim. But for this creature, […]

Antimicrobial Resistance (AMR) research at the Quadram Institute

Antimicrobial resistance is a global problem caused by bacteria which develop resistance to antimicrobial drugs. This is a serious life-threatening issue, as treating infections and safely performing routine medical procedures could become impossible. The Quadram Institute is contributing to the battle against AMR, but we need a coordinated coordinated global approach based on the One […]

A World Without Microbes: An Apocalyptic Thought Experiment | I Contain Multitudes

[MUSIC PLAYING] ED YONG: Imagine wiping out every microbe on Earth, every bacteria, every germ. I’ve done that. That is Professor Jack Gilbert from the University of Chicago. Catastrophic ideas are exciting. Everyone loves a disaster movie. ED: This summer– JACK GILBERT: As a microbe guy, you’ll like this movie. ED: In a world without […]

How antibiotics work

How do antibiotics work? Pathogenic bacteria in the body cause infections, which can be treated by antibiotics Bacteriostatic antibiotics slow the growth of bacteria by interfering with the processes the bacteria need to multiply These processes include: DNA replication Metabolism e.g. enzyme activity Protein production Bactericidal antibiotics kill the bacteria, for example by preventing the […]

Your Microbiome: The Invisible Creatures That Keep You Alive!

[SHOW OPENING MUSIC] This episode was sponsored by Audible. [OPENING SHOW MUSIC] Teleport every one of your cells into the next room, and you’d leave a strange shadow behind. A ghostly cloud of single-celled creatures that live on and inside your body. Your microbiome. Zoom in and we can see this cloud is made of […]

Is The Future Of Antibiotics At The Bottom Of The Ocean?

[MUSIC PLAYING] NARRATOR: Off the coast of California, scientists from UC Santa Cruz are scouring the ocean for what they hope is the key to fighting a new breed of drug-resistant superbugs. BRYSON VOIRIN: So we’re out here in Monterey Bay looking for the next potential medical breakthrough. But how are we going to do […]